You will most likely get some kind of negative response for mentioning 22s on these forums. It also isn't my cup of tea either. However, if the shoe fits, lace that ish up.
As for fit, there are few things you'd need to consider. With bigger wheels, especially 22s, even if you run some kind of super lowpro rubber band tire setup, you're likely going to face some kind of inner fender rubbing issues. It might also interfere with your knuckle, upper control arm, and etc. As for 20s, you'll most likely have less issues to worry about and I'm sure there are plenty of people whom are running such setup.
On top of the overall diameter of the wheels + tires, you'd also have to consider the offset of the wheels (to get better clearance and overall poke out or in look of the wheels). Sometimes, depending on the diameter, even if you don't lower the car, the added diameter from wheel+tire may also fill up the wheel gap. If you choose to stay at factory diameter, and choose to lower the car, you'd also have to rectify the negative camber that comes with lowering your vehicle.
What I'm trying to say is that there are so many variables that no matter which way you want to take your setup, some careful calculation and measurement will definitely come a long way for you.
GOOD LUCK!